Recently we switched to wildcard SSL certificate & our on premise exchange services were configured to use the new certificate from ECP. Then, we upgraded our Antivirus software on the Exchange server and needed a reboot.

Once after the physical reboot, Exchange services completely looked toasted. Although the users were able to logon to OWA, after authentication it was just blank, empty pages. We are using Microsoft Exchange 2013 and a quick search landed us on this page.

As per instructions provided by Microsoft, we found out that the IIS “Exchange Back End” site didn’t have the SSL certificate assigned. Once after assigning the new wildcard certificate, we restarted IIS and all services came online immediately after that.