I started using Windows 10 from the early developer previews & was lucky until yesterday (24th June 2020). Few things didn’t work as expected then onwards.
I noticed the troubles when I clicked on the network icon on the taskbar, which usually pops up a window from which I can connect to another available connection or turn “Airplane Mode” on or off etc
Unfortunately, this has stopped on me all of a sudden. I started searching for a solution & came across few, which didn’t solve my issues. Today morning 25th June 2020, I noticed that it was not just the network connection icon, my clock and action center also had the same issue of not responding to mouse clicks!
Please refer the above links for situation those may not be fixed by the below simple instruction. While trying to find a solution, accidently I landed on the below settings area & toggled the “Get notifications from apps and other senders” from on to off & then reversed it.
That was it! Toggling Notifications on and off has brought back the functionality to whole those icons which were not responding. Give it a try and let me know whether it helped you! (No need to restart the computer)